What do calcium channel blockers primarily do?

Calcium channel blockers are primarily known for their ability to relax and widen blood vessels, which leads to vasodilation of arteries. This is achieved by preventing calcium from entering the muscle cells of the heart and blood vessels, which is essential for muscle contraction. When these channels are blocked, the smooth muscle cells in the arterial walls relax, resulting in the dilation of the arteries. This vasodilation helps lower blood pressure and reduces the workload on the heart.

Furthermore, calcium channel blockers also have the effect of decreasing heart rate, which is beneficial in managing conditions such as hypertension and certain types of angina. By lowering both the blood pressure and heart rate, these medications help improve overall cardiovascular function and reduce the risk of complications related to high blood pressure.

In summary, calcium channel blockers achieve significant therapeutic effects by facilitating vasodilation of arteries and decreasing heart rate, making them essential in the treatment of various cardiovascular conditions.